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The Ormdl genes regulate the sphingolipid synthesis pathway to ensure proper myelination and neurologic function in mice
Sphingolipids are membrane and bioactive lipids that are required for many aspects of normal mammalian development and physiology. However, the importance of the regulatory mechanisms that control sphingolipid levels in these processes is not well understood. The mammalian ORMDL proteins (ORMDL1, 2...
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| 出版年: | eLife |
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| 主要な著者: | , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6934382/ https://ncbi.nlm.nih.gov/pubmed/31880535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51067 |
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