The Ormdl genes regulate the sphingolipid synthesis pathway to ensure proper myelination and neurologic function in mice

Sphingolipids are membrane and bioactive lipids that are required for many aspects of normal mammalian development and physiology. However, the importance of the regulatory mechanisms that control sphingolipid levels in these processes is not well understood. The mammalian ORMDL proteins (ORMDL1, 2...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Clarke, Benjamin A, Majumder, Saurav, Zhu, Hongling, Lee, Y Terry, Kono, Mari, Li, Cuiling, Khanna, Caroline, Blain, Hailey, Schwartz, Ronit, Huso, Vienna L, Byrnes, Colleen, Tuymetova, Galina, Dunn, Teresa M, Allende, Maria L, Proia, Richard L
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Biochemistry and Chemical Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934382/
https://ncbi.nlm.nih.gov/pubmed/31880535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51067
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