Janus Kinase 2 (JAK2) Dissociates Hepatosteatosis from Hepatocellular Carcinoma in Mice

Hepatocellular carcinoma is an end-stage complication of non-alcoholic fatty liver disease (NAFLD). Inflammation plays a critical role in the progression of non-alcoholic fatty liver disease and the development of hepatocellular carcinoma. However, whether steatosis per se promotes liver cancer, and...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Shi, Sally Yu, Luk, Cynthia T., Schroer, Stephanie A., Kim, Min Jeong, Dodington, David W., Sivasubramaniyam, Tharini, Lin, Lauren, Cai, Erica P., Lu, Shun-Yan, Wagner, Kay-Uwe, Bazinet, Richard P., Woo, Minna
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2017
Matèries:
Molecular Bases of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339761/
https://ncbi.nlm.nih.gov/pubmed/28100771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.752519
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