Hepatocyte-specific Deletion of Janus Kinase 2 (JAK2) Protects against Diet-induced Steatohepatitis and Glucose Intolerance

Non-alcoholic fatty liver disease (NAFLD) is becoming the leading cause of chronic liver disease and is now considered to be the hepatic manifestation of the metabolic syndrome. However, the role of steatosis per se and the precise factors required in the progression to steatohepatitis or insulin re...

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Autores principales: Shi, Sally Yu, Martin, Rubén García, Duncan, Robin E., Choi, Diana, Lu, Shun-Yan, Schroer, Stephanie A., Cai, Erica P., Luk, Cynthia T., Hopperton, Kathryn E., Domenichiello, Anthony F., Tang, Christine, Naples, Mark, Dekker, Mark J., Giacca, Adria, Adeli, Khosrow, Wagner, Kay-Uwe, Bazinet, Richard P., Woo, Minna
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Metabolism
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323042/
https://ncbi.nlm.nih.gov/pubmed/22275361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.317453
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