Hepatocyte-specific Deletion of Janus Kinase 2 (JAK2) Protects against Diet-induced Steatohepatitis and Glucose Intolerance

Non-alcoholic fatty liver disease (NAFLD) is becoming the leading cause of chronic liver disease and is now considered to be the hepatic manifestation of the metabolic syndrome. However, the role of steatosis per se and the precise factors required in the progression to steatohepatitis or insulin re...

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Main Authors: Shi, Sally Yu, Martin, Rubén García, Duncan, Robin E., Choi, Diana, Lu, Shun-Yan, Schroer, Stephanie A., Cai, Erica P., Luk, Cynthia T., Hopperton, Kathryn E., Domenichiello, Anthony F., Tang, Christine, Naples, Mark, Dekker, Mark J., Giacca, Adria, Adeli, Khosrow, Wagner, Kay-Uwe, Bazinet, Richard P., Woo, Minna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323042/
https://ncbi.nlm.nih.gov/pubmed/22275361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.317453
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