Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions

Strict regulation of stem cell metabolism is essential for tissue functions and tumor suppression. In this study, we investigated the role of fumarate hydratase (Fh1), a key component of the mitochondrial tricarboxylic acid (TCA) cycle and cytosolic fumarate metabolism, in normal and leukemic hemato...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Exp Med
Main Authors: Guitart, Amelie V., Panagopoulou, Theano I., Villacreces, Arnaud, Vukovic, Milica, Sepulveda, Catarina, Allen, Lewis, Carter, Roderick N., van de Lagemaat, Louie N., Morgan, Marcos, Giles, Peter, Sas, Zuzanna, Gonzalez, Marta Vila, Lawson, Hannah, Paris, Jasmin, Edwards-Hicks, Joy, Schaak, Katrin, Subramani, Chithra, Gezer, Deniz, Armesilla-Diaz, Alejandro, Wills, Jimi, Easterbrook, Aaron, Coman, David, So, Chi Wai Eric, O’Carroll, Donal, Vernimmen, Douglas, Rodrigues, Neil P., Pollard, Patrick J., Morton, Nicholas M., Finch, Andrew, Kranc, Kamil R.
פורמט: Artigo
שפה:Inglês
יצא לאור: The Rockefeller University Press 2017
נושאים:
Research Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339674/
https://ncbi.nlm.nih.gov/pubmed/28202494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161087
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