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Biochemical characterization and essentiality of Plasmodium fumarate hydratase

Plasmodium falciparum (Pf), the causative agent of malaria, has an iron–sulfur cluster–containing class I fumarate hydratase (FH) that catalyzes the interconversion of fumarate to malate, a well-known reaction in the tricarboxylic acid cycle. In humans, the same reaction is catalyzed by class II FH...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Jayaraman, Vijay, Suryavanshi, Arpitha, Kalale, Pavithra, Kunala, Jyothirmai, Balaram, Hemalatha
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912476/
https://ncbi.nlm.nih.gov/pubmed/29449371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.816298
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