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Electrostatic tuning of the pre- and post-hydrolytic open states in CFTR
Cystic fibrosis transmembrane conductance regulator (CFTR) is an ion channel that couples adenosine triphosphate (ATP) hydrolysis at its nucleotide-binding domains to gating transitions in its transmembrane domains. We previously reported that the charge-neutralized mutant R352C shows two distinct o...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Gen Physiol |
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| Κύριοι συγγραφείς: | , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The Rockefeller University Press
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5339510/ https://ncbi.nlm.nih.gov/pubmed/28242630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611664 |
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