Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease

BACKGROUND: Both genetic and lifestyle factors contribute to individual-level risk of coronary artery disease. The extent to which increased genetic risk can be offset by a healthy lifestyle is unknown. METHODS: Using a polygenic score of DNA sequence polymorphisms, we quantified genetic risk for co...

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Detalhes bibliográficos
Publicado no:N Engl J Med
Main Authors: Khera, Amit V., Emdin, Connor A., Drake, Isabel, Natarajan, Pradeep, Bick, Alexander G., Cook, Nancy R., Chasman, Daniel I., Baber, Usman, Mehran, Roxana, Rader, Daniel J., Fuster, Valentin, Boerwinkle, Eric, Melander, Olle, Orho-Melander, Marju, Ridker, Paul M, Kathiresan, Sekar
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338864/
https://ncbi.nlm.nih.gov/pubmed/27959714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1605086
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