Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease

BACKGROUND: Both genetic and lifestyle factors contribute to individual-level risk of coronary artery disease. The extent to which increased genetic risk can be offset by a healthy lifestyle is unknown. METHODS: Using a polygenic score of DNA sequence polymorphisms, we quantified genetic risk for co...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:N Engl J Med
Prif Awduron: Khera, Amit V., Emdin, Connor A., Drake, Isabel, Natarajan, Pradeep, Bick, Alexander G., Cook, Nancy R., Chasman, Daniel I., Baber, Usman, Mehran, Roxana, Rader, Daniel J., Fuster, Valentin, Boerwinkle, Eric, Melander, Olle, Orho-Melander, Marju, Ridker, Paul M, Kathiresan, Sekar
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338864/
https://ncbi.nlm.nih.gov/pubmed/27959714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1605086
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