Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease

BACKGROUND: Both genetic and lifestyle factors contribute to individual-level risk of coronary artery disease. The extent to which increased genetic risk can be offset by a healthy lifestyle is unknown. METHODS: Using a polygenic score of DNA sequence polymorphisms, we quantified genetic risk for co...

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Опубликовано в: :N Engl J Med
Главные авторы: Khera, Amit V., Emdin, Connor A., Drake, Isabel, Natarajan, Pradeep, Bick, Alexander G., Cook, Nancy R., Chasman, Daniel I., Baber, Usman, Mehran, Roxana, Rader, Daniel J., Fuster, Valentin, Boerwinkle, Eric, Melander, Olle, Orho-Melander, Marju, Ridker, Paul M, Kathiresan, Sekar
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338864/
https://ncbi.nlm.nih.gov/pubmed/27959714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1605086
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