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Gata4 potentiates second heart field proliferation and Hedgehog signaling for cardiac septation
GATA4, an essential cardiogenic transcription factor, provides a model for dominant transcription factor mutations in human disease. Dominant GATA4 mutations cause congenital heart disease (CHD), specifically atrial and atrioventricular septal defects (ASDs and AVSDs). We found that second heart fie...
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| I publikationen: | Proc Natl Acad Sci U S A |
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| Huvudupphovsmän: | , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2017
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338429/ https://ncbi.nlm.nih.gov/pubmed/28167794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605137114 |
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