Gata4 potentiates second heart field proliferation and Hedgehog signaling for cardiac septation

GATA4, an essential cardiogenic transcription factor, provides a model for dominant transcription factor mutations in human disease. Dominant GATA4 mutations cause congenital heart disease (CHD), specifically atrial and atrioventricular septal defects (ASDs and AVSDs). We found that second heart fie...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Zhou, Lun, Liu, Jielin, Xiang, Menglan, Olson, Patrick, Guzzetta, Alexander, Zhang, Ke, Moskowitz, Ivan P., Xie, Linglin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2017
Gaiak:
PNAS Plus
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338429/
https://ncbi.nlm.nih.gov/pubmed/28167794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605137114
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