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Tbx5-Hedgehog Molecular Networks Are Essential in the Second Heart Field for Atrial Septation
SUMMARY: The developmental mechanisms underlying human congenital heart disease (CHD) are poorly understood. Atrial septal defects (ASDs) can result from haploinsufficiency of cardiogenic transcription factors including TBX5. We demonstrated that Tbx5 is required in the second heart field (SHF) for...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3912192/ https://ncbi.nlm.nih.gov/pubmed/22898775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.06.006 |
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