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Tbx5-Hedgehog Molecular Networks Are Essential in the Second Heart Field for Atrial Septation

SUMMARY: The developmental mechanisms underlying human congenital heart disease (CHD) are poorly understood. Atrial septal defects (ASDs) can result from haploinsufficiency of cardiogenic transcription factors including TBX5. We demonstrated that Tbx5 is required in the second heart field (SHF) for...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Xie, Linglin, Hoffmann, Andrew D., Burnicka-Turek, Ozanna, Friedland-Little, Joshua M., Zhang, Ke, Moskowitz, Ivan P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912192/
https://ncbi.nlm.nih.gov/pubmed/22898775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.06.006
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