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Tbx5 and Osr1 interact to regulate posterior second heart field cell cycle progression for cardiac septation

RATIONALE: Mutations of TBX5 cause Holt–Oram syndrome (HOS) in humans, a disease characterized by atrial or occasionally ventricular septal defects in the heart and skeletal abnormalities of the upper extremity. Previous studies have demonstrated that Tbx5 regulates Osr1 expression in the second hea...

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Dettagli Bibliografici
Pubblicato in:J Mol Cell Cardiol
Autori principali: Zhou, Lun, Liu, Jielin, Olson, Patrick, Zhang, Ke, Wynne, Joshua, Xie, Linglin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530064/
https://ncbi.nlm.nih.gov/pubmed/25986147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.05.005
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