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Tbx5 and Osr1 interact to regulate posterior second heart field cell cycle progression for cardiac septation

RATIONALE: Mutations of TBX5 cause Holt–Oram syndrome (HOS) in humans, a disease characterized by atrial or occasionally ventricular septal defects in the heart and skeletal abnormalities of the upper extremity. Previous studies have demonstrated that Tbx5 regulates Osr1 expression in the second hea...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Zhou, Lun, Liu, Jielin, Olson, Patrick, Zhang, Ke, Wynne, Joshua, Xie, Linglin
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530064/
https://ncbi.nlm.nih.gov/pubmed/25986147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.05.005
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