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Gene network and familial analyses uncover a gene network involving Tbx5/Osr1/Pcsk6 interaction in the second heart field for atrial septation

Atrial septal defects (ASDs) are a common human congenital heart disease (CHD) that can be induced by genetic abnormalities. Our previous studies have demonstrated a genetic interaction between Tbx5 and Osr1 in the second heart field (SHF) for atrial septation. We hypothesized that Osr1 and Tbx5 sha...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Zhang, Ke K., Xiang, Menglan, Zhou, Lun, Liu, Jielin, Curry, Nathan, Heine Suñer, Damian, Garcia-Pavia, Pablo, Zhang, Xiaohua, Wang, Qin, Xie, Linglin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764195/
https://ncbi.nlm.nih.gov/pubmed/26744331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv636
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