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Tbx5 and Osr1 interact to regulate posterior second heart field cell cycle progression for cardiac septation

RATIONALE: Mutations of TBX5 cause Holt–Oram syndrome (HOS) in humans, a disease characterized by atrial or occasionally ventricular septal defects in the heart and skeletal abnormalities of the upper extremity. Previous studies have demonstrated that Tbx5 regulates Osr1 expression in the second hea...

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Bibliografiska uppgifter
I publikationen:J Mol Cell Cardiol
Huvudupphovsmän: Zhou, Lun, Liu, Jielin, Olson, Patrick, Zhang, Ke, Wynne, Joshua, Xie, Linglin
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530064/
https://ncbi.nlm.nih.gov/pubmed/25986147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.05.005
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