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Mechanism and Timing of Mcm2–7 Ring Closure During DNA Replication Origin Licensing
Opening and closing of two ring-shaped Mcm2–7 DNA helicases is necessary to license eukaryotic origins of replication although the mechanisms controlling these events are unclear. The origin-recognition complex (ORC), Cdc6 and Cdt1 facilitate this process, establishing a topological link between eac...
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| 出版年: | Nat Struct Mol Biol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5336523/ https://ncbi.nlm.nih.gov/pubmed/28191892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3375 |
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