Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resistant states is normalised by the synthetic retinoid Fenretinide in mice

Fibroblast growth factor 21 (FGF21) has emerged as an important beneficial regulator of glucose and lipid homeostasis but its levels are also abnormally increased in insulin-resistant states in rodents and humans. The synthetic retinoid Fenretinide inhibits obesity and improves glucose homeostasis i...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Morrice, Nicola, Mcilroy, George D., Tammireddy, Seshu R., Reekie, Jennifer, Shearer, Kirsty D., Doherty, Mary K., Delibegović, Mirela, Whitfield, Phillip D., Mody, Nimesh
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335663/
https://ncbi.nlm.nih.gov/pubmed/28256636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43782
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