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Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resistant states is normalised by the synthetic retinoid Fenretinide in mice

Fibroblast growth factor 21 (FGF21) has emerged as an important beneficial regulator of glucose and lipid homeostasis but its levels are also abnormally increased in insulin-resistant states in rodents and humans. The synthetic retinoid Fenretinide inhibits obesity and improves glucose homeostasis i...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Morrice, Nicola, Mcilroy, George D., Tammireddy, Seshu R., Reekie, Jennifer, Shearer, Kirsty D., Doherty, Mary K., Delibegović, Mirela, Whitfield, Phillip D., Mody, Nimesh
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335663/
https://ncbi.nlm.nih.gov/pubmed/28256636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43782
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