Učitavanje...
Neuronal human BACE1 knockin induces systemic diabetes in mice
AIMS: β-Secretase 1 (BACE1) is a key enzyme in Alzheimer’s disease pathogenesis that catalyses the amyloidogenic cleavage of amyloid precursor protein (APP). Recently, global Bace1 deletion was shown to protect against diet-induced obesity and diabetes, suggesting that BACE1 is a potential regulator...
Spremljeno u:
| Izdano u: | Diabetologia |
|---|---|
| Glavni autori: | , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Springer Berlin Heidelberg
2016
|
| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4901117/ https://ncbi.nlm.nih.gov/pubmed/27138913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-016-3960-1 |
| Oznake: |
Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|