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The Rotavirus NSP4 Viroporin Domain is a Calcium-conducting Ion Channel

Viroporins are small virus-encoded ion channel proteins. Most viroporins are monovalent selective cation channels, with few showing the ability to conduct divalent cations, like calcium (Ca(2+)). Nevertheless, some viroporins are known to disrupt host cell Ca(2+) homeostasis, which is critical for v...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pham, Thieng, Perry, Jacob L., Dosey, Timothy L., Delcour, Anne H., Hyser, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335360/
https://ncbi.nlm.nih.gov/pubmed/28256607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43487
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