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Autophagy hijacked through viroporin-activated calcium/calmodulin-dependent kinase kinase-β signaling is required for rotavirus replication

Autophagy is a cellular degradation process involving an intracellular membrane trafficking pathway that recycles cellular components or eliminates intracellular microbes in lysosomes. Many pathogens subvert autophagy to enhance their replication, but the mechanisms these pathogens use to initiate t...

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Bibliographic Details
Main Authors: Crawford, Sue E., Hyser, Joseph M., Utama, Budi, Estes, Mary K.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528557/
https://ncbi.nlm.nih.gov/pubmed/23184977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216539109
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