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Rotavirus Disrupts Calcium Homeostasis by NSP4 Viroporin Activity
Many viruses alter intracellular calcium homeostasis. The rotavirus nonstructural protein 4 (NSP4), an endoplasmic reticulum (ER) transmembrane glycoprotein, increases intracellular levels of cytoplasmic Ca(2+) ([Ca(2+)]cyto) through a phospholipase C-independent pathway, which is required for virus...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Microbiology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2999940/ https://ncbi.nlm.nih.gov/pubmed/21151776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00265-10 |
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