Structural Plasticity of the Coiled-Coil Domain of Rotavirus NSP4

Rotavirus (RV) nonstructural protein 4 (NSP4) is a virulence factor that disrupts cellular Ca(2+) homeostasis and plays multiple roles regulating RV replication and the pathophysiology of RV-induced diarrhea. Although its native oligomeric state is unclear, crystallographic studies of the coiled-coi...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Sastri, Narayan P., Viskovska, Maria, Hyser, Joseph M., Tanner, Mark R., Horton, Lori B., Sankaran, Banumathi, Prasad, B. V. Venkataram, Estes, Mary K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Structure and Assembly
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248954/
https://ncbi.nlm.nih.gov/pubmed/25231315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02227-14
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