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Homocysteine modulates 5‐lipoxygenase expression level via DNA methylation

Elevated levels of homocysteinemia (Hcy), a risk factor for late‐onset Alzheimer's disease (AD), have been associated with changes in cell methylation. Alzheimer's disease is characterized by an upregulation of the 5‐lipoxygenase (5LO), whose promoter is regulated by methylation. However,...

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Bibliografiset tiedot
Julkaisussa:Aging Cell
Päätekijät: Li, Jian‐Guo, Barrero, Carlos, Gupta, Sapna, Kruger, Warren D., Merali, Salim, Praticò, Domenico
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334532/
https://ncbi.nlm.nih.gov/pubmed/27896923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12550
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