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Homocysteine modulates 5‐lipoxygenase expression level via DNA methylation
Elevated levels of homocysteinemia (Hcy), a risk factor for late‐onset Alzheimer's disease (AD), have been associated with changes in cell methylation. Alzheimer's disease is characterized by an upregulation of the 5‐lipoxygenase (5LO), whose promoter is regulated by methylation. However,...
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| Pubblicato in: | Aging Cell |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5334532/ https://ncbi.nlm.nih.gov/pubmed/27896923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12550 |
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