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Elevated levels of brain homocysteine directly modulates the pathological phenotype of a mouse model of tauopathy
High circulating level of homocysteine (Hcy), also known as hyper-homocysteinemia, is a risk factor for Alzheimer’s disease (AD). Previous studies showed that elevated Hcy promotes brain amyloidosis and behavioral deficits in mouse models of AD. However, whether it also directly modulates the develo...
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| Publicat a: | Mol Psychiatry |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6215750/ https://ncbi.nlm.nih.gov/pubmed/29728702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0062-0 |
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