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Five lipoxygenase hypomethylation mediates the homocysteine effect on Alzheimer’s phenotype
Environmental and genetic risk factors are implicated in the pathogenesis of Alzheimer’s disease (AD). However, how they interact and influence its pathogenesis remains to be investigated. High level of homocysteine (Hcy) is an AD risk factor and associates with an up-regulation of the ALOX5 gene. I...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5382538/ https://ncbi.nlm.nih.gov/pubmed/28383037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46002 |
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