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Homocysteine modulates 5‐lipoxygenase expression level via DNA methylation

Elevated levels of homocysteinemia (Hcy), a risk factor for late‐onset Alzheimer's disease (AD), have been associated with changes in cell methylation. Alzheimer's disease is characterized by an upregulation of the 5‐lipoxygenase (5LO), whose promoter is regulated by methylation. However,...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Aging Cell
Prif Awduron: Li, Jian‐Guo, Barrero, Carlos, Gupta, Sapna, Kruger, Warren D., Merali, Salim, Praticò, Domenico
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334532/
https://ncbi.nlm.nih.gov/pubmed/27896923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12550
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