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Sequential Designs for Individualized Dosing in Phase I Cancer Clinical Trials
This paper addresses dose finding in clinical trials where individuals exhibit biologic characteristics that alter the toxicity risks of the individuals. In these situations, instead of determining a dose that works for every patient, the trial aims to identify a dosing algorithm that prescribes dos...
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| Vydáno v: | Contemp Clin Trials |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5332400/ https://ncbi.nlm.nih.gov/pubmed/27592121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2016.08.018 |
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