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Stochastic Approximation and Modern Model-based Designs for Dose-Finding Clinical Trials

In 1951 Robbins and Monro published the seminal paper on stochastic approximation and made a specific reference to its application to the “estimation of a quantal using response, non-response data”. Since the 1990s, statistical methodology for dose-finding studies has grown into an active area of re...

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Detalhes bibliográficos
Autor principal: Cheung, Ying Kuen
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010381/
https://ncbi.nlm.nih.gov/pubmed/21197369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1214/10-STS334
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