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A dose–schedule finding design for phase I–II clinical trials
Dose-finding methods aiming at identifying an optimal dose of a treatment with a given schedule may be at a risk of misidentifying the best treatment for patients. In this article we propose a phase I/II clinical trial design to find the optimal dose-schedule combination. We define schedule as the m...
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| Udgivet i: | J R Stat Soc Ser C Appl Stat |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4747255/ https://ncbi.nlm.nih.gov/pubmed/26877554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/rssc.12113 |
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