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A Bayesian Dose-finding Design for Phase I/II Clinical Trials with Non-ignorable Dropouts
Phase I/II trials utilize both toxicity and efficacy data to achieve efficient dose finding. However, due to the requirement of assessing efficacy outcome, which often takes a long period of time to be evaluated, the duration of phase I/II trials is often longer than that of the conventional dose-fi...
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| Publicado no: | Stat Med |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4390488/ https://ncbi.nlm.nih.gov/pubmed/25626676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6443 |
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