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Bayesian Phase I/II Biomarker-based Dose Finding for Precision Medicine with Molecularly Targeted Agents
The optimal dose for treating patients with a molecularly targeted agent may differ according to the patient’s individual characteristics, such as biomarker status. In this article, we propose a Bayesian phase I/II dose-finding design to find the optimal dose that is personalized for each patient ac...
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| Publicado no: | J Am Stat Assoc |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7451208/ https://ncbi.nlm.nih.gov/pubmed/32863478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01621459.2016.1228534 |
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