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Intravascular hemolysis and the pathophysiology of sickle cell disease
Hemolysis is a fundamental feature of sickle cell anemia that contributes to its pathophysiology and phenotypic variability. Decompartmentalized hemoglobin, arginase 1, asymmetric dimethylarginine, and adenine nucleotides are all products of hemolysis that promote vasomotor dysfunction, proliferativ...
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| Veröffentlicht in: | J Clin Invest |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5330745/ https://ncbi.nlm.nih.gov/pubmed/28248201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI89741 |
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