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Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling
Tissue inflammation is a key component of obesity-induced insulin resistance, with a variety of immune cell types accumulating in adipose tissue. Here, we have demonstrated increased numbers of B2 lymphocytes in obese adipose tissue and have shown that high-fat diet–induced (HFD-induced) insulin res...
Guardat en:
| Publicat a: | J Clin Invest |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5330737/ https://ncbi.nlm.nih.gov/pubmed/28192375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90350 |
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