SRC ONCOGENE INDUCES TROP2 PROTEOLYTIC ACTIVATION VIA CYCLIN D1

Proteomic analysis of castration-resistant prostate cancer demonstrated the enrichment of SRC tyrosine kinase activity in approximately ninety percent of patients. Src is known to induce cyclin D1, and a cyclin D1-regulated gene expression module predict poor outcome in human prostate cancer. The tu...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cancer Res
Autors principals: Ju, Xiaoming, Jiao, Xuanmao, Ertel, Adam, Casimiro, Mathew C., Di Sante, Gabriele, Deng, Shengqiong, Li, Zhiping, Di Rocco, Agnese, Zhan, Tingting, Hawkins, Adam, Stoyanova, Tanya, Ando, Sebastiano, Fatatis, Alessandro, Lisanti, Michael P., Gomella, Leonard G., Languino, Lucia R., Pestell, Richard G.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330252/
https://ncbi.nlm.nih.gov/pubmed/27634768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-3327
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars