SRC ONCOGENE INDUCES TROP2 PROTEOLYTIC ACTIVATION VIA CYCLIN D1

Proteomic analysis of castration-resistant prostate cancer demonstrated the enrichment of SRC tyrosine kinase activity in approximately ninety percent of patients. Src is known to induce cyclin D1, and a cyclin D1-regulated gene expression module predict poor outcome in human prostate cancer. The tu...

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Detaylı Bibliyografya
Yayımlandı:Cancer Res
Asıl Yazarlar: Ju, Xiaoming, Jiao, Xuanmao, Ertel, Adam, Casimiro, Mathew C., Di Sante, Gabriele, Deng, Shengqiong, Li, Zhiping, Di Rocco, Agnese, Zhan, Tingting, Hawkins, Adam, Stoyanova, Tanya, Ando, Sebastiano, Fatatis, Alessandro, Lisanti, Michael P., Gomella, Leonard G., Languino, Lucia R., Pestell, Richard G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330252/
https://ncbi.nlm.nih.gov/pubmed/27634768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-3327
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