CCR5 receptor antagonists block metastasis to bone of v-Src-oncogene-transformed metastatic prostate cancer cell lines

Src family kinases (SFKs) integrate signal transduction for multiple receptors, regulating cellular proliferation invasion and metastasis in human cancer. Although Src is rarely mutated in human prostate cancer, SFK activity is increased in the majority of human prostate cancers. In order to determi...

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Bibliographic Details
Published in:Cancer Res
Main Authors: Sicoli, Daniela, Jiao, Xuanmao, Ju, Xiaoming, Velasco-Velazquez, Marco, Ertel, Adam, Addya, Sankar, Li, Zhiping, Ando, Sebastiano, Fatatis, Alessandro, Paudyal, Bishnuhari, Cristofanilli, Massimo, Thakur, Mathew L., Lisanti, Michael P, Pestell, Richard G.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294544/
https://ncbi.nlm.nih.gov/pubmed/25452256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-0612
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