CCR5 receptor antagonists block metastasis to bone of v-Src-oncogene-transformed metastatic prostate cancer cell lines

Src family kinases (SFKs) integrate signal transduction for multiple receptors, regulating cellular proliferation invasion and metastasis in human cancer. Although Src is rarely mutated in human prostate cancer, SFK activity is increased in the majority of human prostate cancers. In order to determi...

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Détails bibliographiques
Publié dans:Cancer Res
Auteurs principaux: Sicoli, Daniela, Jiao, Xuanmao, Ju, Xiaoming, Velasco-Velazquez, Marco, Ertel, Adam, Addya, Sankar, Li, Zhiping, Ando, Sebastiano, Fatatis, Alessandro, Paudyal, Bishnuhari, Cristofanilli, Massimo, Thakur, Mathew L., Lisanti, Michael P, Pestell, Richard G.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294544/
https://ncbi.nlm.nih.gov/pubmed/25452256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-0612
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