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Opportunities for Translation from the Bench: Therapeutic Intervention of the JAK/STAT Pathway in Neuroinflammatory Diseases
Pathogenic CD4(+) T cells and myeloid cells play critical roles in the pathogenesis of multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE), an animal model of MS. These immune cells secrete aberrantly high levels of pro-inflammatory cytokines that pathogenically bridge the in...
Tallennettuna:
| Julkaisussa: | Crit Rev Immunol |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5328657/ https://ncbi.nlm.nih.gov/pubmed/27279046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1615/CritRevImmunol.2016015517 |
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