Therapeutic Efficacy of Suppressing the JAK/STAT Pathway in Multiple Models of EAE()

Pathogenic T helper cells and myeloid cells are involved in the pathogenesis of Multiple Sclerosis (MS) and Experimental Autoimmune Encephalomyelitis (EAE), an animal model of MS. The JAK/STAT pathway is utilized by numerous cytokines for signaling, and is critical for development, regulation and te...

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Autors principals: Liu, Yudong, Holdbrooks, Andrew T., De Sarno, Patrizia, Rowse, Amber L., Yanagisawa, Lora L., McFarland, Braden C., Harrington, Laurie E., Raman, Chander, Sabbaj, Steffanie, Benveniste, Etty N., Qin, Hongwei
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934829/
https://ncbi.nlm.nih.gov/pubmed/24323580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301513
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