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Enantioselective Total Synthesis of (+)-Amphirionin-4

An enantioselective total synthesis of (+)-amphirionin-4 has been accomplished in a convergent manner. The synthesis features an efficient enzymatic lipase resolution to access the tetrahydrofuranol core in optically-active form. The functionalized tetrahydrofuran derivative was synthesized via an o...

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Pubblicato in:Org Lett
Autori principali: Ghosh, Arun K., Nyalapatla, Prasanth R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328589/
https://ncbi.nlm.nih.gov/pubmed/27116318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b00942
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