Polyubiquitinylation Profile in Down Syndrome Brain Before and After the Development of Alzheimer Neuropathology

Aims: Among the putative mechanisms proposed to be common factors in Down syndrome (DS) and Alzheimer's disease (AD) neuropathology, deficits in protein quality control (PQC) have emerged as a unifying mechanism of neurodegeneration. Considering that disturbance of protein degradation systems i...

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Détails bibliographiques
Publié dans:Antioxid Redox Signal
Auteurs principaux: Tramutola, Antonella, Di Domenico, Fabio, Barone, Eugenio, Arena, Andrea, Giorgi, Alessandra, di Francesco, Laura, Schininà, Maria Eugenia, Coccia, Raffaella, Head, Elizabeth, Butterfield, D. Allan, Perluigi, Marzia
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2017
Sujets:
Forum Original Research Communication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327052/
https://ncbi.nlm.nih.gov/pubmed/27627691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2016.6686
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