Numb-like (NumbL) downregulation increases tumorigenicity, cancer stem cell-like properties and resistance to chemotherapy

NumbL, or Numb-like, is a close homologue of Numb, and is part of an evolutionary conserved protein family implicated in some important cellular processes. Numb is a protein involved in cell development, in cell adhesion and migration, in asymmetric cell division, and in targeting proteins for endoc...

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Bibliographic Details
Published in:Oncotarget
Main Authors: García-Heredia, José M., Sivianes, Eva M. Verdugo, Lucena-Cacace, Antonio, Molina-Pinelo, Sonia, Carnero, Amancio
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325389/
https://ncbi.nlm.nih.gov/pubmed/27613838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11553
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