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Role of the Holoenzyme PP1-SPN in the Dephosphorylation of the RB Family of Tumor Suppressors During Cell Cycle

SIMPLE SUMMARY: Cell cycle progression is highly regulated by modulating the phosphorylation status of retinoblastoma (RB) family proteins. This process is controlled by a balance in the action of kinases, such as the complexes formed by cyclin-dependent kinases (CDKs) and cyclins, and phosphatases,...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Verdugo-Sivianes, Eva M., Carnero, Amancio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8124259/
https://ncbi.nlm.nih.gov/pubmed/34066428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13092226
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