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Proteasome-dependent, ubiquitin-independent degradation of the Rb family of tumor suppressors by the human cytomegalovirus pp71 protein

Most of the substrates degraded by the proteasome are marked with polyubiquitin chains. However, there are a limited number of examples of nonubiquitinated proteins that are degraded by the proteasome. Here, we describe the degradation of the retinoblastoma family of tumor suppressor proteins by the...

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Detalhes bibliográficos
Main Authors: Kalejta, Robert F., Shenk, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152280/
https://ncbi.nlm.nih.gov/pubmed/12626766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0538058100
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