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Proteasome-dependent, ubiquitin-independent degradation of the Rb family of tumor suppressors by the human cytomegalovirus pp71 protein

Most of the substrates degraded by the proteasome are marked with polyubiquitin chains. However, there are a limited number of examples of nonubiquitinated proteins that are degraded by the proteasome. Here, we describe the degradation of the retinoblastoma family of tumor suppressor proteins by the...

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Autori principali: Kalejta, Robert F., Shenk, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC152280/
https://ncbi.nlm.nih.gov/pubmed/12626766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0538058100
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