Mutation of SPINOPHILIN (PPP1R9B) found in human tumors promotes the tumorigenic and stemness properties of cells

Rationale: SPINOPHILIN (SPN, PPP1R9B) is an important tumor suppressor involved in the progression and malignancy of different tumors depending on its association with protein phosphatase 1 (PP1) and the ability of the PP1-SPN holoenzyme to dephosphorylate retinoblastoma (pRB). Methods: We performed...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Theranostics
Main Authors: Verdugo-Sivianes, Eva M, Rojas, Ana M, Muñoz-Galván, Sandra, Otero-Albiol, Daniel, Carnero, Amancio
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2021
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7847670/
https://ncbi.nlm.nih.gov/pubmed/33537097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.53572
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