Acquisition of an oncogenic fusion protein serves as an initial driving mutation by inducing aneuploidy and overriding proliferative defects

While many solid tumors are defined by the presence of a particular oncogene, the role that this oncogene plays in driving transformation through the acquisition of aneuploidy and overcoming growth arrest are often not known. Further, although aneuploidy is present in many solid tumors, it is not cl...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Loupe, Jacob M., Miller, Patrick J., Bonner, Benjamin P., Maggi, Elaine C., Vijayaraghavan, Jyothi, Zabaleta, Jovanny, Taylor, Christopher M., Tsien, Fern, Crabtree, Judy S., Hollenbach, Andrew D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Priority Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325330/
https://ncbi.nlm.nih.gov/pubmed/27588498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11716
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