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α-catenin overrides Src-dependent activation of β-catenin oncogenic signaling

Loss of α-catenin is one of the characteristics of prostate cancer. The catenins (α, β) associated with E-cadherin play a critical role in the regulation of cell-cell adhesion. Tyrosine phosphorylation of β-catenin dissociates it from E-cadherin and facilitates its entry into the nucleus, where β-ca...

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Detalhes bibliográficos
Main Authors: Inge, Landon J., Rajasekaran, Sigrid A., Wolle, Daniel, Barwe, Sonali P., Ryazantsev, Sergey, Ewing, Charles M., Isaacs, William B., Rajasekaran, Ayyappan K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527861/
https://ncbi.nlm.nih.gov/pubmed/18566211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-07-2029
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