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Na,K-ATPase β-subunit cis homo-oligomerization is necessary for epithelial lumen formation in mammalian cells

Na,K-ATPase is a hetero-oligomer of an α- and a β-subunit. The α-subunit (Na,K-α) possesses the catalytic function, whereas the β-subunit (Na,K-β) has cell-cell adhesion function and is localized to the apical junctional complex in polarized epithelial cells. Earlier, we identified two distinct cons...

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Detalhes bibliográficos
Main Authors: Barwe, Sonali P., Skay, Anna, McSpadden, Ryan, Huynh, Thu P., Langhans, Sigrid A., Inge, Landon J., Rajasekaran, Ayyappan K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575706/
https://ncbi.nlm.nih.gov/pubmed/23077177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.108795
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