Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase β(1)-subunit

Na,K-ATPase is composed of two essential α- and β-subunits, both of which have multiple isoforms. Evidence indicates that the Na,K-ATPase enzymatic activity as well as its α(1), α(3) and β(1) isoforms are reduced in the failing human heart. The catalytic α-subunit is the receptor for cardiac glycosi...

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Autores principales: Barwe, Sonali P., Jordan, Maria C., Skay, Anna, Inge, Landon, Rajasekaran, Sigrid A., Wolle, Daniel, Johnson, Christina L., Neco, Patricia, Fang, Kun, Rozengurt, Nora, Goldhaber, Joshua I., Roos, Kenneth P., Rajasekaran, Ayyappan K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749246/
https://ncbi.nlm.nih.gov/pubmed/19683723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.07.018
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